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RTC – Team Research and Development
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PD Dr. med. Nan Ma
(group leader research and development)
Phone: +49 (0)381 - 4 94 61 05
nan.ma@med.uni-rostock.de
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Nan Ma, associate professor, has been a principal investigator and group leader since 2004 at FKGO Labs of the Department of Cardiac Surgery (University of Rostock) that was integrated in the RTC in 2009. Furthermore Nan Ma is an executive board member of the RTC. Prior to joining Rostock group, she worked on the development of the targeted gene delivery/therapy vector of central nerve system in the Institute of Bionanotechnology (IBN), National University of Singapore..
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Nan Ma received her Ph.D. degree in molecular biology from National University of Singapore in 2003. She finished her Master in immunology and M.D. from Peking Union Medical College and Norman Bethune Medical University in 1998 and 1994. Her research interests include stem cell mediated cardiac repair and cardiac regeneration. Her stem cell research involves studies of adult stem cell physiology, aging of stem cells, and stem cell tumor formation, seeking to understand the mechanism of stem cell mediated cardiac repair and develop tissue engineering based stem cell therapies for the cardiac diseases.
The specific aims of her current studies are to (1) determine the role of SDF-1/CXCR4 axis in stem cell migration and angiogenesis effects; (2) determine the differentiation potential of stem cell (CD133 EPC, MSCs) and the interaction of stem cell with host tissue; (3) the real-time dynamics of stem cell endothelial interaction by fluorescence intravital microscopy. In 2006, she received the Hancock Prize from the German Society of Cardio-Thoracic Surgery for her work related to the area. She demonstrated that human cord blood mononuclear cells could directional migrate to the infarcted heart subsequently after the SDF-1α early upregulation in the damaged area 24 hours after LAD ligation. SDF-1 might be an important chemokine for stem cell mediated cardiac therapy.
Her second major area of research involves studies of development of the nonviral polymeric gene vector for stem cell modification; development of the biofunctional scaffold for stem cell proliferation and cardiac regeneration. Her work related to the use nonviral polymeric gene vector has resulted in several patents.
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Dr. Jun Li
(group leader research and development)
Phone: +49 (0)381 - 4 94 61 05
jun.li@med.uni-rostock.de
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Jun Li is a group leader in research and development at the RTC.
He initially studied medicine in China (Dalian) and subsequently at the University of Kiel, where he gained his MD. He then pursued research in cellular immunology and molecular cardiology at the University of Mainz and Free University of Berlin. From 2002 to 2009, he worked as a group leader dealing with adaptive protective mechanisms against ischemic injury in the brain and heart at the Center for Cardiovascular Research and Institute of Pharmacology at the Charité – Universitätsmedizin Berlin. His team first recognised and established that angiotensin AT2 receptor protects against cerebral ischemia-induced neuronal injury. One of Jun Li’s important contributions was to introduce modern cellular techniques to elucidate the cardioprotective mechanisms. In 2005, he was awarded the Dieter-Klaus-Förderpreis für Hypertonieforschung of the German Hypertension Society for his innovative concepts exploring the interaction of angiotensin AT2 receptor and T lymphocytes in the heart.
Since January 2010, Jun Li he has been working at the RTC. A main focus of his current research is the elucidation of the adaptive protective mechanisms of cell biology and the impact of these cellular mechanisms on the outcomes of cardiovascular disease. His research efforts are guided by the translational perspectives.
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Dr. Cornelia Lux (postdoc)
Phone +49 (0)381 - 4 94 61 05
cornelia.lux@uni-rostock.de
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Cornelia Lux has started working at RTC as a postdoc in October 2009. She focuses on fundamental research concerning modification of stem cells and is a specialist for descriptive and functional analysis of cellular ATMPs for clinical use.
Cornelia Lux studied pharmacy at Johannes Gutenberg-University Mainz and University of Bourgogne Dijon. For her research on the cytotoxicity of modified atherogenic LDL towards immune cells done she received a PhD in 2009.
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| Dr. Hoang Tu-Rapp (postdoc)
Phone: +49 (0)381 - 4 94 61 05
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Hoang Tu-Rapp studied Nutritional Sciences at Bonn University. After completing her Ph.D. in immunolgy at the Institute for Physiology and Comparative Immunology at Bonn University and the Institute of Immunology at Rostock University she gained experience in several clinical research groups at the medical faculty of Rostock University including work on autoimmune diseases and mouse genetic. |
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| Evgenya Delyagina (PhD student)
Phone: +49 (0)381 - 4 94 61 05
evgenya.delyagina@med.uni-rostock.de
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Evgenya Delyagina was born in Saint - Petersburg, Russia in 1986. She studied Pharmacy in St.Petersburg State Chemical - Pharmaceutical Academy and graduated in 2008.
Since January, 2009 she is writing PhD thesis at the University of Rostock, Medical Faculty. Her study is focused on non-viral gene delivery to mammalian cells via polymer vectors and magnetic nanopraticles.
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| Peter Mark (PhD student)
Phone: +49 (0)381 - 4 94 61 05
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Yue Zhang (PhD student)
Phone: +49 (0)381 - 4 94 61 05
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Yue Zhang was born in 1982 in Tianjin P.R.China. He graduated on biology engineering from Tianjin Univ of Science&Technology in 2005. And then he gained the master degree on biology and chemistry engineering from Tianjin Univ of Science & Technology on May, 2008. |
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Anna Skorska (PhD student)
Phone: +49 (0)381 - 4 94 61 05
anna.skorska@med.uni-rostock.de
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Anna Skorska started her PhD project at the Center for Cardiovascular Research of the Charité – Universitätsmedizin Berlin in July 2008, and she has been working in research and development at the RTC since 2010.
Anna Skorska received her Master degree in Biotechnology at the University of Technology in Wroclaw. Her research interest is concentrated on the adaptive cellular mechanisms for cardioprotection, with special attention to the interaction of cardiac various cell populations including T lymphocytes, and stem cells.
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Marion Ludwig (PhD student)
Phone: +49 (0)381 - 4 94 61 05
marion.ludwig@med.uni-rostock.de
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Marion Ludwig started her PhD in May 2010 in the group of Jun Li in Research and Development at the RTC.
She studied medical Biotechnology at the Wageningen University, Netherlands, where she received her Master of Science.
The main focus of her study is the investigation of the importance of c-kit progenitor cells in myocardial infarction. This includes the research on simultaneous expression and influence of the angiotensin-II receptor type 2.
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Anita Tölk (Project staff)
Phone: +49 (0)381 - 4 94 61 05
anita.toelk@med.uni-rostock.de |
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Anita Tölk studied biology at University of Rostock and received her diploma degree in 2010. During her diploma thesis she investigated the differentiation and proliferation potential of murine hematopoietic stem cells.
Having finished her study in 2010 Anita Tölk has been to the research group of RTC. Currently, she is involved in several research projects. In detail she studies the differentiation potential of human and murine bone marrow stem cells and characterises murine cardiac stem cells.
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Margit Fritsche (technician)
Phone: +49 (0)381 - 4 94 61 05
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Margit Fritsche is working as technician at the research group of the RTC. Since January 2005 she is working at the research lab of the Cardiac surgery of the University of Rostock (FKGO). She is responsible for all aspects of the Lan management, including ordering and storing of the materials, technical documentation, controlling and support of different research projects (cell culture etc) and quality management.
Margit Fritsche has a degree as Diploma engineer. She studied at the Humboldt-University of Berlin. She was working for 14 years in different departments for R&D and standardization.
After specialization at the field of Biotechnology she started working at the research group of the Cardiac surgery at the University of Rostock.
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Former employees
Dr. Lailiang Ou
Lailiang Ou worked as a postdoctoral researcher at the RTC from 2009 to 2010. In October 2010 he returned to Nankai University in Tianjin, China, where he works at the key laboratory of bioactive materials.
Dr. Dario Furlani
In 2010 Dario Furlani finished his PhD on the topic “Stem cells therapy after myocardial infarction: direct application or drug-mediated recruitment?” at the RTC. In early 2011 he changed to Carl Zeiss MicroImaging.
Dr. Koji Hirano
Koji Hirano worked as a postdoctoral researcher at the RTC from 2009 to 2011. In May 2011 he returned to Mie University, Tsu, Japan.
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