| Prof. Dr. Gustav Steinhoff and his team have been focussing on research and therapeutical applications of autologous stem cells in cardial surgery for many years.
In the  research and development-branch of the RTC there are currently three research groups which work on the efficacy and safety of stem cells. Corresponding activities are:
- Investigation of the mechanism of stem cells in the myocardium applying genomic and proteomic analysis techniques
- Review of efficacy and safety of applied human bone-marrow-derived CD133+ stem cells in animal models
- Basic research regarding stem cell differentiation
These topics are closely associated with the planned clinical multicentric Phase III study which has been investigated by Rostock to prove the efficacy and safety of the cardiac stem cell therapy. This study is performed at three centers, i.e., at the Clinic and Policlinic for Cardiac Surgery of Rostock, at the German Heart Institute Berlin and at the Hannover Medical School.
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